Ohta’s Isan and Ohta’s Isan <Sachet>, staple gastrointestinal medicines in Japanese households, are rebranding as Ohta’s Isan S and Ohta’s Isan <Sachet> S. The packaging has been redesigned, and the ingredients have been improved.

Let’s start with the packaging. The new design features an “S” added to “Ohta’s Isan.” The label and text colors are brighter, giving it a more refined and friendly appearance. When displayed on drugstore shelves, the new packaging is easily distinguishable, making it more recognizable to travelers when they first see it.

The increased number of doses for both the cans and sachets is another key feature of the renewed products. Ohta’s Isan S is now available in cans containing 80 g or 150 g, while the convenient travel-size Ohta’s Isan <Sachet> S comes in doses of 18, 34, or 50. You can choose the type that best suits your lifestyle: cans are ideal for household storage, while sachets are perfect for carrying when going out or traveling.

Please note that some stores may still have the previous medicines in stock immediately after October 2025, so you may find both versions on the same shelves.

Along with the design, the ingredients used in Ohta’s IsanS and Ohta’s Isan <Sachet> S have also improved. Compared to the previous versions, both products now offer enhanced acid-neutralizing capacity to neutralize excess acid reflux and improved digestive properties.

First, let’s focus on the enhanced acid-neutralizing capacity of the medicines. Excess acid reflux from eating too many sweets, greasy foods, or drinking too much alcohol can lead to heartburn and stomach discomfort.

With Ohta’s Isan S and Ohta’s Isan <Sachet> S, the improved formulation of the antacids provides approximately 32.5%* greater acid-neutralizing capacity compared to the previous versions. This helps alleviate stomach discomfort and provides greater relief in various everyday situations.

The improved digestive properties of the medicines are also worth noting. Difficulty digesting food due to age or an unbalanced diet can cause indigestion and loss of appetite. The increased number of digestive enzymes in the new formula enhances digestion by approximately 12.5%(*) compared to the previous product. This makes it an even more recommended gastrointestinal medicine for those times when you want to thoroughly enjoy your meals.

Ohta’s Isan S and Ohta’s Isan <Sachet> S can be taken to alleviate heartburn or indigestion, or when you want to make eating meals more comfortable.

(*: Calculated based on hypothetical value compared to Ohta’s Isan.)

The improved Ohta’s Isan S and Ohta’s Isan <Sachet> S maintain their qualities that have made the brand the preferred choice to many people over the years.

First, they feature a balanced blend of seven kinds of stomachic herbs (cinnamon bark, fennel, nutmeg, clove, citrus unshiu peel, gentian, and powdered Picrasma wood) that help regulate weakened gastrointestinal function, soothe stomach discomfort, and stimulate appetite. This formula, which makes use of nature’s benefits, has been cultivated for over 145 years and remains cherished today.

Next, the unique powder manufacturing method preserves the herbs’ natural aroma and flavor, enhanced with l-menthol to provide a refreshing sensation upon ingestion, making it easy to drink. The refreshing sensation unique to Ohta’s Isan remains unchanged even after rebranding.

Additionally, the product is still available in both cans and sachets. Cans are ideal for household storage, while sachets are convenient to carry in a bag when going out, allowing you to select the option best suited to your lifestyle.

Ohta’s Isan S and Ohta’s Isan <Sachet> S are compound gastrointestinal medicines suitable for a variety of common stomach conditions. They are widely used to relieve heartburn, stomach oppression, and stomach discomfort caused by overdrinking, overeating, as well as to address loss of appetite, hyperacidity, and nausea caused by hangovers.

• Overdrinking, heartburn, stomach discomfort
• Weak stomach, stomach oppression, overeating, stomachache
• Indigestion, for promote digestion, loss of appetite, hyperacidity
• Feeling of fullness in the stomach and abdomen, nausea (stomach retching, retching due to hangovers and overdrinking, feeling of sickness)
• Vomiting, heaviness in the chest, belching, stomach heaviness

Ohta’s Isan S (can)
・15 years and over : 1.3 g per dose (one spoonful of the provided spoon), up to three times a day
・8-14 years : 0.65 g per dose (half a spoonful), up to three times a day
・Under 8 years : Not to be taken

Ohta’s Isan ＜Sachet＞ S (sachet)
・15 years and over : One sachet, up to three times a day
・8-14 years : Half a sachet, up to three times a day
・Under 8 years : Not to be taken

Take both medicines with water or lukewarm water either after or two to three hours between meals.

In addition to the rebranding, we also want to introduce you to Ohtainyan, Ohta’s Isan’s official PR ambassador, a male blue calico cat. It is said that only one in 30,000 cats is born a male calico. There is even a legend that says meeting Ohtainyan brings good luck due to his blue coat. His unique and charming appearance is making him popular as a mascot, helping to promote the appeal of Ohta’s Isan.

Check the latest information on Ohtainyan’s official social media

Starting October 2025, Ohta’s Isan and Ohta’s Isan <Sachet> have rebranded as Ohta’s Isan S and Ohta’s Isan <Sachet> S. The packaging features brighter colors on both the label and text. The cans are now available in 80 g or 150 g sizes, while the sachets come in doses of 18, 34, or 50. An “S” has been added to the product names to clearly indicate in stores that these are new versions.

If you are in Japan, you can find them at drugstores or pharmacies. You will surely be pleased to spot the new packaging on store shelves. On your next trip to Japan, be sure to look for the updated Ohta’s Isan with an “S” after their names.